Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 4/20 | 0.67 |
| ▸ | IAPP | P10997 | 3/20 | 0.64 |
| ▸ | MMP2 | P08253 | 4/20 | 0.53 |
| ▸ | MMP9 | P14780 | 3/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | MMP8 | P22894 | 1/20 | 0.53 |
| ▸ | APP | P05067 | 2/20 | 0.49 |
| ▸ | AKR1B10 | O60218 | 3/20 | 0.48 |
| ▸ | AKR1B1 | P15121 | 3/20 | 0.48 |
| ▸ | TTR | P02766 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | MMP1 | P03956 | 2/20 | 0.48 |
| ▸ | AKR1C3 | P42330 | 2/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695492 | 0.91 | ALOX5 (0.58) | ALOX5IAPPMMP2MMP9NFKB1 | |
| SCHEMBL8392957 | 0.87 | IAPP (0.74) | ALOX5IAPPMMP2MMP9NFKB1 | |
| SCHEMBL29489693 | 0.87 | IAPP (0.74) | ALOX5IAPPMMP2MMP9NFKB1 | |
| SCHEMBL8392954 | 0.87 | IAPP (0.74) | ALOX5IAPPMMP2MMP9NFKB1 | |
| SCHEMBL9535674 | 0.84 | ALOX5 (0.49) | ALOX5IAPPMMP2MMP9NFKB1 | |
| SCHEMBL9535670 | 0.84 | ALOX5 (0.49) | ALOX5IAPPMMP2MMP9NFKB1 | |
| SCHEMBL29689081 | 0.83 | ALOX5 (0.67) | ALOX5IAPPMMP2MMP9NFKB1 | |
| SCHEMBL14964001 | 0.83 | ALOX5 (0.67) | ALOX5IAPPMMP2MMP9NFKB1 | |
| SCHEMBL8847826 | 0.82 | APP (0.72) | ALOX5IAPPMMP2MMP9NFKB1 | |
| SCHEMBL8847830 | 0.82 | APP (0.72) | ALOX5IAPPMMP2MMP9NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5142095-A | Treating inflammation, allergies, asthma, cardiovascular disorders, psoriasis | WARNER-LAMBERT COMPANY (US) | 1992-08-25 | — | — | US | claimed |