Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNF | P01375 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | GBA1 | P04062 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694188 | 0.82 | TNF (0.38) | TNFHTTTSHRL3MBTL1MAPK1 | |
| Hydrochloric Acid SCHEMBL9757671 | 0.81 | TNF (0.37) | TNFHTTTSHRL3MBTL1MAPK1 | |
| SCHEMBL10437081 | 0.75 | CA12 (0.42) | TNFHTTTSHRMAPK1KMT2A | |
| SCHEMBL454595 | 0.74 | TNF (0.44) | TNFHTTTSHRL3MBTL1MAPK1 | |
| SCHEMBL9792931 | 0.73 | KDM4E (0.41) | TNFHTTTSHRL3MBTL1MAPK1 | |
| SCHEMBL7805222 | 0.73 | TSHR (0.40) | TNFTSHRL3MBTL1KDM4EMAPT | |
| SCHEMBL8031008 | 0.72 | TSHR (0.39) | TNFHTTTSHRL3MBTL1MAPK1 | |
| SCHEMBL9826827 | 0.72 | ALDH1A1 (0.42) | TNFHTTTSHRL3MBTL1KMT2A | |
| Hydrochloric Acid SCHEMBL9793004 | 0.72 | KDM4E (0.40) | TNFHTTTSHRL3MBTL1KMT2A | |
| SCHEMBL9525237 | 0.72 | CYP3A4 (0.47) | TNFKMT2AMAPTCYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370880-B1 | TRIALKOXY-SUBSTITUTED M-PHENYLENE DIAMINES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS COUPLING AGENTS IN THE OXIDATION DYEING OF KERATINIC FIBRES, ESPECIALLY HUMAN HAIR | L'OREAL (FR) | 1992-11-11 | — | — | EP | claimed |
| US-5002585-A | HAIR DYES, USED WITH PHENYLENEDIAMINES, AMINOPHENOLS AND AMINOPYRIDINES | L'OREAL (FR) | 1991-03-26 | — | — | US | claimed |
| EP-0370880-A1 | Trialkoxy-substituted m-phenylene diamines, process for their preparation, and their use as coupling agents in the oxidation dyeing of keratinic fibres, especially human hair | L'OREAL (FR) | 1990-05-30 | — | — | EP | claimed |
| EP-0370880-B1 | TRIALKOXY-SUBSTITUTED M-PHENYLENE DIAMINES, PROCESS FOR THEIR PREPARATION, AND THEIR USE AS COUPLING AGENTS IN THE OXIDATION DYEING OF KERATINIC FIBRES, ESPECIALLY HUMAN HAIR | L'OREAL (FR) | 1992-11-11 | — | — | EP | disclosed |