Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | TUBB4A | P04350 | 2/20 | 0.44 |
| ▸ | TUBB | P07437 | 2/20 | 0.44 |
| ▸ | TUBA3C | P0DPH7 | 2/20 | 0.44 |
| ▸ | TUBA1B | P68363 | 2/20 | 0.44 |
| ▸ | TUBA4A | P68366 | 2/20 | 0.44 |
| ▸ | TUBB4B | P68371 | 2/20 | 0.44 |
| ▸ | TUBB3 | Q13509 | 2/20 | 0.44 |
| ▸ | TUBB2A | Q13885 | 2/20 | 0.44 |
| ▸ | TUBB8 | Q3ZCM7 | 2/20 | 0.44 |
| ▸ | TUBA3E | Q6PEY2 | 2/20 | 0.44 |
| ▸ | TUBA1A | Q71U36 | 2/20 | 0.44 |
| ▸ | TUBA1C | Q9BQE3 | 2/20 | 0.44 |
| ▸ | TUBB6 | Q9BUF5 | 2/20 | 0.44 |
| ▸ | TUBB2B | Q9BVA1 | 2/20 | 0.44 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23011878 | 0.84 | MAPT (0.50) | CYP3A4MAPTSMN1; SMN2PTGS2TUBB4A | |
| SCHEMBL12963092 | 0.82 | PTGS2 (0.50) | CYP3A4MAPTSMN1; SMN2PTGS2TUBB4A | |
| SCHEMBL4587193 | 0.81 | PTGS2 (0.44) | CYP3A4MAPTSMN1; SMN2PTGS2TUBB4A | |
| SCHEMBL28801415 | 0.81 | HTR2A (0.53) | CYP3A4MAPTPTGS2TUBB4ATUBB | |
| SCHEMBL8348474 | 0.79 | KDM4E (0.51) | MAPTSMN1; SMN2MEN1KMT2ACYP2C9 | |
| SCHEMBL18243936 | 0.79 | MEN1 (0.39) | CYP3A4MAPTSMN1; SMN2TUBB4ATUBB | |
| SCHEMBL3207404 | 0.79 | POLB (0.54) | CYP3A4MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL2759516 | 0.78 | PTGS2 (0.54) | CYP3A4MAPTSMN1; SMN2PTGS2TUBB4A | |
| SCHEMBL13590550 | 0.77 | MAPT (0.47) | CYP3A4MAPTSMN1; SMN2PTGS2TUBB4A | |
| SCHEMBL5162466 | 0.77 | POLB (0.44) | SMN1; SMN2TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0301751-B1 | PYRIDINIUM DERIVATIVES, THEIR PRODUCTION AND USE | Takeda Chemical Industries, Ltd. (JP) | 1993-03-10 | — | — | EP | disclosed |
| US-4962113-A | PLATELET ACTIVATING FACTOR ANTAGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD (JP) | 1990-10-09 | — | — | US | disclosed |
| EP-0301751-A1 | Pyridinium derivatives, their production and use | Takeda Chemical Industries, Ltd. (JP) | 1989-02-01 | — | — | EP | disclosed |