Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 5/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | APAF1 | O14727 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | SAE1 | Q9UBE0 | 1/20 | 0.44 |
| ▸ | UBA2 | Q9UBT2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | MITF | O75030 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694470 | 1.00 | GAA (0.50) | GAAMAPTKDM4EAPAF1NSD2 | |
| SCHEMBL9732218 | 0.89 | GAA (0.45) | GAAMAPTKDM4EAPAF1NSD2 | |
| SCHEMBL9422717 | 0.86 | GAA (0.49) | GAAMAPTKDM4EAPAF1NSD2 | |
| SCHEMBL9422716 | 0.86 | GAA (0.49) | GAAMAPTKDM4EAPAF1NSD2 | |
| SCHEMBL9735339 | 0.86 | MAPT (0.50) | GAAMAPTKDM4EAPAF1NSD2 | |
| SCHEMBL9732486 | 0.86 | SLC2A1 (0.50) | GAAMAPTKDM4EAPAF1NSD2 | |
| SCHEMBL9732722 | 0.83 | CTSA (0.41) | GAAMAPTKDM4EMAPK1MEN1 | |
| SCHEMBL9382970 | 0.83 | CTSA (0.41) | GAAMAPTKDM4EMAPK1MEN1 | |
| SCHEMBL9732677 | 0.83 | KMT2A (0.51) | GAAMAPTKDM4EMAPK1MEN1 | |
| SCHEMBL9733071 | 0.82 | ALDH1A1 (0.49) | GAAKDM4ESMN1; SMN2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013846-A1 | PYRIMIDINYL- AND TRIAZINYLSALICYL- AND -PICOLINYLALDEHYDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-08-20 | — | — | WO | claimed |
| US-5167693-A | Pre- and postemergence | BAYER AKTIENGESELLSCHAFT (DE) | 1992-12-01 | — | — | US | disclosed |
| WO-1992013846-A1 | PYRIMIDINYL- AND TRIAZINYLSALICYL- AND -PICOLINYLALDEHYDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-08-20 | — | — | WO | disclosed |
| EP-0459243-A2 | Substituted Azines | BAYER AG (DE) | 1991-12-04 | — | — | EP | disclosed |