Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9694470 | 0.86 | GAA (0.50) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL9694473 | 0.86 | GAA (0.50) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL9732967 | 0.82 | MAPT (0.53) | MAPTSMN1; SMN2POLBCYP1A2CYP3A4 | |
| SCHEMBL12417113 | 0.82 | MAPT (0.53) | MAPTSMN1; SMN2POLBCYP1A2CYP3A4 | |
| SCHEMBL9732218 | 0.82 | GAA (0.45) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL9732965 | 0.82 | MAPT (0.53) | MAPTSMN1; SMN2POLBCYP1A2CYP3A4 | |
| SCHEMBL9732591 | 0.80 | KDM4E (0.66) | MAPTRAB9ANPC1SMN1; SMN2MEN1 | |
| SCHEMBL9733071 | 0.77 | ALDH1A1 (0.49) | SMN1; SMN2LMNAGAAKDM4EL3MBTL1 | |
| SCHEMBL9733068 | 0.77 | ALDH1A1 (0.49) | SMN1; SMN2LMNAGAAKDM4EL3MBTL1 | |
| SCHEMBL9732486 | 0.75 | SLC2A1 (0.50) | MAPTRAB9ANPC1SMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992013846-A1 | PYRIMIDINYL- AND TRIAZINYLSALICYL- AND -PICOLINYLALDEHYDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-08-20 | — | — | WO | claimed |
| WO-1992013846-A1 | PYRIMIDINYL- AND TRIAZINYLSALICYL- AND -PICOLINYLALDEHYDE DERIVATIVES | CIBA-GEIGY AG (CH) | 1992-08-20 | — | — | WO | disclosed |