⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9693628 | 0.93 | AGTR1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL9310132 | 0.91 | — | — | |
| SCHEMBL9859908 | 0.91 | AGTR1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL9309853 | 0.90 | AGTR1 (0.31) | — | |
| SCHEMBL9695697 | 0.90 | PPARG (0.34) | — | |
| SCHEMBL9694855 | 0.88 | AGTR1 (0.35) | — | |
| SCHEMBL9694921 | 0.87 | HPGD (0.31) | — | |
| SCHEMBL9695403 | 0.87 | AGTR1 (0.30) | — | |
| Hydrochloric Acid SCHEMBL9310047 | 0.86 | AGTR1 (0.33) | — | |
| SCHEMBL9693579 | 0.86 | PPARG (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992016552-A1 | 1-IMIDAZOLGEMETHYL BENZOFURAN DERIVATIVES AS INHIBITORS OF ANGIOTENSIN II ACTIVITY | GLAXO GROUP LIMITED (GB) | 1992-10-01 | — | — | WO | claimed |
| EP-0505954-A1 | N-Imidazolylmethyl benzofuran derivatives as inhibitors of angiotensin II activity | GLAXO GROUP LIMITED (GB) | 1992-09-30 | — | — | EP | claimed |
| WO-1992016552-A1 | 1-IMIDAZOLGEMETHYL BENZOFURAN DERIVATIVES AS INHIBITORS OF ANGIOTENSIN II ACTIVITY | GLAXO GROUP LIMITED (GB) | 1992-10-01 | — | — | WO | disclosed |
| EP-0505954-A1 | N-Imidazolylmethyl benzofuran derivatives as inhibitors of angiotensin II activity | GLAXO GROUP LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |