SCHEMBL9694899

SCHEMBL9694899

Fc1cc(F)c2cccc(CBr)c2c1

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 3/20 0.34
CYP19A1 P11511 1/20 0.33
HPRT1 P00492 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9695725 0.79 TAAR1 (0.48)
SCHEMBL9695718 0.77 SLC6A4 (0.42) GPR84CYP19A1
SCHEMBL7558378 0.74 HPRT1 (0.40) GPR84CYP19A1HPRT1
SCHEMBL2141182 0.73 GABRA1 (0.38)
SCHEMBL3276551 0.73 CYP1A2 (0.43) GPR84CYP19A1
SCHEMBL9695274 0.72 GPR84 (0.32) GPR84
SCHEMBL4166534 0.72 SLC11A2 (0.41)
SCHEMBL4015859 0.72
SCHEMBL30306116 0.71 DAO (0.42) GPR84HPRT1
SCHEMBL3594153 0.71 DAO (0.42) GPR84HPRT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5112851-A Agricultural Fungicides SANDOZ LTD. (CH) 1992-05-12 US disclosed
US-4939148-A Amine derivatives, processes for their production and their use SANDOZ, LTD. (CH) 1990-07-03 US disclosed