Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.46 |
| ▸ | CES1 | P23141 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9151459 | 0.81 | DAO (0.61) | ALDH1A1F2DAOGSK3BMAPT | |
| SCHEMBL11708498 | 0.81 | MAOA (0.58) | ALDH1A1LMNAF2DAOGSK3B | |
| SCHEMBL15197217 | 0.81 | SMN1; SMN2 (0.50) | ALDH1A1LMNAF2DAOGSK3B | |
| SCHEMBL15979690 | 0.80 | KMT2A (0.54) | ALDH1A1LMNAF2DAOGSK3B | |
| SCHEMBL9144815 | 0.80 | F2 (0.70) | ALDH1A1LMNAF2DAOGSK3B | |
| SCHEMBL11703462 | 0.78 | F2 (0.44) | ALDH1A1LMNAF2DAOGSK3B | |
| SCHEMBL9695549 | 0.77 | GSK3B (0.47) | ALDH1A1LMNAF2DAOGSK3B | |
| SCHEMBL11705547 | 0.77 | PTGS2 (0.58) | ALDH1A1LMNAF2DAOMAPT | |
| SCHEMBL11705557 | 0.77 | PTGS2 (0.58) | ALDH1A1LMNAF2DAOMAPT | |
| SCHEMBL4286491 | 0.76 | MAOA (0.59) | ALDH1A1LMNAF2DAOSRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5112851-A | Agricultural Fungicides | SANDOZ LTD. (CH) | 1992-05-12 | — | — | US | disclosed |
| US-4939148-A | Amine derivatives, processes for their production and their use | SANDOZ, LTD. (CH) | 1990-07-03 | — | — | US | disclosed |