Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 5/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.71 |
| ▸ | RAB9A | P51151 | 5/20 | 0.71 |
| ▸ | HPGD | P15428 | 5/20 | 0.71 |
| ▸ | NPC1 | O15118 | 4/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.71 |
| ▸ | BACE1 | P56817 | 1/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.71 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | NOS3 | P29474 | 1/20 | 0.52 |
| ▸ | NOS1 | P29475 | 1/20 | 0.52 |
| ▸ | NOS2 | P35228 | 1/20 | 0.52 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695371 | 0.85 | TP53 (0.64) | TP53SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL6475635 | 0.82 | RAB9A (0.68) | TP53SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL9693713 | 0.82 | TP53 (0.63) | TP53SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL9695295 | 0.80 | TP53 (0.67) | TP53SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL10574131 | 0.76 | CYP1A2 (0.72) | TP53SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL9693793 | 0.75 | TP53 (0.60) | TP53SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL29278179 | 0.74 | TP53 (1.00) | TP53SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL9012067 | 0.73 | HDAC1 (0.46) | TP53SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL9693721 | 0.73 | PDE5A (0.42) | TP53SMN1; SMN2RAB9AHPGDNPC1 | |
| SCHEMBL9012301 | 0.72 | LMNA (0.42) | TP53SMN1; SMN2RAB9AHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5106976-A | Antisecretory agents | NIPPON CHEMIPHAR CO., LTD. (JP) | 1992-04-21 | — | — | US | disclosed |
| US-4933458-A | ANTISECRETORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1990-06-12 | — | — | US | disclosed |