Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 6/20 | 0.44 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 6/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7833447 | 0.86 | TBXA2R (0.44) | TP53KDM4EMAPTKAT2BLMNA | |
| SCHEMBL7832090 | 0.86 | L3MBTL1 (0.44) | TP53HTR3EHTR3BHTR1AHTR2C | |
| SCHEMBL7835831 | 0.84 | CYP11B1 (0.46) | TP53CYP1A2CYP2C19KDM4ELMNA | |
| SCHEMBL7834654 | 0.78 | HTT (0.49) | CYP2C19KDM4EMAPTLMNAMEN1 | |
| SCHEMBL1650533 | 0.78 | RAB9A (0.48) | TP53HTR3EHTR3BHTR1AHTR2C | |
| SCHEMBL7833661 | 0.76 | PDE10A (0.37) | TP53LMNAMEN1PABPC1KMT2A | |
| SCHEMBL30932218 | 0.74 | TP53 (0.66) | TP53HTR3EHTR3BHTR1AHTR2C | |
| SCHEMBL9696462 | 0.74 | TP53 (0.66) | TP53HTR3EHTR3BHTR1AHTR2C | |
| SCHEMBL17966778 | 0.72 | TP53 (0.54) | TP53MAPTLMNAENPP2RXFP1 | |
| SCHEMBL15654857 | 0.71 | TP53 (0.33) | TP53KDM4EENPP2MEN1PABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006086-A1 | NOVEL 4-PIPERIDINYLCARBONYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-04-16 | — | — | WO | disclosed |