Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12947881 | 0.85 | ALDH1A1 (0.40) | ALDH1A1SOS1MITFPKMPOLB | |
| SCHEMBL12920050 | 0.82 | ALDH1A1 (0.37) | ALDH1A1SOS1MITFPKMSMN1; SMN2 | |
| SCHEMBL14079856 | 0.75 | ALDH1A1 (0.39) | ALDH1A1SOS1MITFPKMPOLB | |
| SCHEMBL969711 | 0.70 | MITF (0.36) | ALDH1A1MITFPOLBHTTSMN1; SMN2 | |
| SCHEMBL63286 | 0.69 | ALDH1A1 (0.59) | ALDH1A1SOS1MITFPKMPOLB | |
| SCHEMBL10460856 | 0.68 | CYP1A2 (0.38) | ALDH1A1SOS1PKMPOLBSMN1; SMN2 | |
| SCHEMBL971068 | 0.66 | MGAM (0.32) | — | |
| SCHEMBL971872 | 0.66 | MEN1 (0.36) | PKMPOLB | |
| SCHEMBL5353581 | 0.66 | MITF (0.46) | ALDH1A1SOS1MITFPKMPOLB | |
| SCHEMBL8443810 | 0.65 | ALDH1A1 (0.41) | ALDH1A1MITFPKMPOLBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7871982-B2 | Lincomycin derivatives and antimicrobial agents comprising the same as active ingredient | MEIJI SEIKA KAISHA, LTD. (JP) | 2011-01-18 | — | — | US | disclosed |
| US-20090156512-A1 | potent activity against resistant pneumococci | MEIJI SEIKA KAISHA, LTD. (JP) | 2009-06-18 | — | — | US | disclosed |
| EP-1970377-A1 | LINCOMYCIN DERIVATIVE AND ANTIBACTERIAL AGENT CONTAINING THE SAME AS ACTIVE INGREDIENT | MEIJI SEIKA KAISHA LTD. (JP) | 2008-09-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090156512-A1 | potent activity against resistant pneumococci | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, NAT1, NPM1 | ALDH1A1 2976/4885SOS1 1355/4885MITF 3728/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.