Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGES | O14684 | 4/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.42 |
| ▸ | TSPO | P30536 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | MGLL | Q99685 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9695395 | 0.77 | POLB (0.56) | PTGESALDH1A1KDM4EL3MBTL1HTT | |
| SCHEMBL9694185 | 0.77 | RAD52 (0.56) | PTGESALDH1A1KDM4EMAPTTP53 | |
| Hydrochloric Acid SCHEMBL9694192 | 0.75 | ALDH1A1 (0.61) | PTGESALDH1A1NPSR1KDM4ETDP1 | |
| SCHEMBL11742743 | 0.73 | ALDH1A1 (0.49) | PTGESALDH1A1NPSR1KDM4ELMNA | |
| SCHEMBL1305249 | 0.73 | ALDH1A1 (0.51) | PTGESALDH1A1NPSR1KDM4ELMNA | |
| SCHEMBL9548089 | 0.72 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNATDP1L3MBTL1 | |
| SCHEMBL21852751 | 0.71 | ALDH1A1 (0.67) | ALDH1A1NPSR1KDM4ELMNATDP1 | |
| Hydrochloric Acid SCHEMBL9695711 | 0.71 | KDM4E (0.47) | ALDH1A1KDM4ETDP1CYP3A4CYP2C9 | |
| Anitrazafen SCHEMBL43419 | 0.71 | ALDH1A1 (0.53) | PTGESALDH1A1NPSR1KDM4ELMNA | |
| SCHEMBL1305539 | 0.71 | ALDH1A1 (0.56) | PTGESALDH1A1NPSR1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002513-A1 | HETEROCYCLIC COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |