Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | PTGES | O14684 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11872551 | 0.89 | MAPT (0.54) | ALDH1A1KDM4ELMNANPSR1TDP1 | |
| SCHEMBL1306494 | 0.80 | MAPT (0.66) | ALDH1A1KDM4ELMNANPSR1TDP1 | |
| SCHEMBL21852751 | 0.80 | ALDH1A1 (0.67) | ALDH1A1KDM4ELMNANPSR1TDP1 | |
| SCHEMBL11237449 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNANPSR1TDP1 | |
| SCHEMBL1305539 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNANPSR1TDP1 | |
| Anitrazafen SCHEMBL43419 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNANPSR1TDP1 | |
| Anitrazafen SCHEMBL30901204 | 0.79 | ALDH1A1 (0.53) | ALDH1A1KDM4ELMNANPSR1TDP1 | |
| SCHEMBL13108714 | 0.79 | ALDH1A1 (0.56) | ALDH1A1KDM4ELMNANPSR1TDP1 | |
| SCHEMBL10817240 | 0.79 | ALDH1A1 (0.55) | ALDH1A1KDM4ELMNANPSR1TDP1 | |
| SCHEMBL1305606 | 0.78 | KDM4E (0.51) | ALDH1A1KDM4ELMNANPSR1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8053573-B2 | Monomer 5, 6-diphenyl-1.2.4-traizinic derivatives and the use thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2011-11-08 | — | — | US | disclosed |
| US-8053573-B2 | Monomer 5, 6-diphenyl-1.2.4-traizinic derivatives and the use thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2011-11-08 | — | — | US | disclosed |
| US-8053573-B2 | Monomer 5, 6-diphenyl-1.2.4-traizinic derivatives and the use thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2011-11-08 | — | — | US | disclosed |
| EP-1751122-B1 | MONOMER 5,6-DIPHENYL-1,2,4-TRIAZINIC DERIVATIVES AND THE USE THEREOF | FABRE PIERRE DERMO COSMETIQUE (FR) | 2010-03-17 | — | — | EP | disclosed |
| US-20080299055-A1 | Monomer 5, 6-Diphenyl-1.2.4-Traizinic Derivatives and the Use Thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2008-12-04 | — | — | US | disclosed |
| US-20080299055-A1 | Monomer 5, 6-Diphenyl-1.2.4-Traizinic Derivatives and the Use Thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2008-12-04 | — | — | US | disclosed |
| US-20080299055-A1 | Monomer 5, 6-Diphenyl-1.2.4-Traizinic Derivatives and the Use Thereof | PIERRE FABRE DERMO-COSMETIQUE (FR) | 2008-12-04 | — | — | US | disclosed |
| US-4190725-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1980-02-26 | — | — | US | disclosed |
| US-4021553-A | 5,6-Diaryl-1,2,4-triazines as topically-active anti-inflammatory agents | ELI LILLY AND COMPANY (US) | 1977-05-03 | — | — | US | disclosed |
| US-4008232-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1977-02-15 | — | — | US | disclosed |
| US-3989831-A | Topically-active anti-inflammatory 3-chloro-5,6-diaryl-1,2,4-triazines | ELI LILLY AND COMPANY (US) | 1976-11-02 | — | — | US | disclosed |
| US-3979516-A | Anti-inflammatory 3-amino-5,6-diaryl-1,2,4-triazines | ELI LILLY AND COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
| US-3948894-A | ANTIINFLAMMATORY | ELI LILLY AND COMPANY (US) | 1976-04-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080299055-A1 | Monomer 5, 6-Diphenyl-1.2.4-Traizinic Derivatives and the Use Thereof | POT1, TELO2, CLIC1 | ALDH1A1 581/4885KDM4E 3517/4885LMNA 526/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.