SCHEMBL9695830

SCHEMBL9695830

CC(C)(C)c1ccc(C(=O)Nc2ccccc2-c2ccccc2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.64
L3MBTL1 Q9Y468 2/20 0.64
NPC1 O15118 1/20 0.64
GLA P06280 1/20 0.64
RAB9A P51151 1/20 0.64
ATM Q13315 1/20 0.64
NR1H4 Q96RI1 2/20 0.62
CA1 P00915 1/20 0.59
CA2 P00918 1/20 0.59
GRIN2C Q14957 1/20 0.59
MAPT P10636 3/20 0.57
RECQL P46063 1/20 0.57
PPARG P37231 2/20 0.56
KCNK9 Q9NPC2 1/20 0.56
KDM4E B2RXH2 3/20 0.56
LMNA P02545 1/20 0.55
KMT2A Q03164 1/20 0.55
CYP1A2 P05177 1/20 0.54
CYP3A4 P08684 1/20 0.54
CYP2D6 P10635 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21652189 0.89 NPC1 (0.66) ALDH1A1L3MBTL1NPC1GLARAB9A
SCHEMBL5223315 0.85 RAB9A (0.73) ALDH1A1L3MBTL1NPC1GLARAB9A
SCHEMBL29434803 0.85 ALDH1A1 (0.66) ALDH1A1L3MBTL1ATMMAPTKDM4E
SCHEMBL12470503 0.85 ALDH1A1 (0.66) ALDH1A1L3MBTL1ATMMAPTKDM4E
SCHEMBL4741129 0.84 TACR1 (0.51) ALDH1A1L3MBTL1NPC1GLARAB9A
Ammonia Solution, Strong SCHEMBL29194251 0.84 ALDH1A1 (0.64) ALDH1A1L3MBTL1ATMMAPTKDM4E
SCHEMBL28442225 0.81 HDAC1 (0.61) ALDH1A1L3MBTL1MAPTKDM4ELMNA
SCHEMBL22388748 0.81 TRPV1 (0.56) ALDH1A1L3MBTL1NPC1GLARAB9A
SCHEMBL6059859 0.81 KMT2A (0.64) ALDH1A1L3MBTL1NPC1RAB9AMAPT
SCHEMBL15561067 0.81 F10 (0.74) ALDH1A1L3MBTL1NPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5135949-A Anticoagulants BOEHRINGER MANNHEIM GMBH (DE) 1992-08-04 US disclosed