Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 12/20 | 0.49 |
| ▸ | DRD4 | P21917 | 4/20 | 0.49 |
| ▸ | DRD2 | P14416 | 3/20 | 0.49 |
| ▸ | DRD3 | P35462 | 3/20 | 0.49 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5539534 | 1.00 | HRH3 (0.49) | HRH3DRD4DRD2DRD3ALDH3A1 | |
| SCHEMBL9697553 | 1.00 | HRH3 (0.49) | HRH3DRD4DRD2DRD3ALDH3A1 | |
| SCHEMBL9697050 | 1.00 | HRH3 (0.49) | HRH3DRD4DRD2DRD3ALDH3A1 | |
| SCHEMBL5534932 | 0.98 | DRD4 (0.50) | HRH3DRD4DRD2DRD3ALDH3A1 | |
| SCHEMBL5540021 | 0.92 | DRD4 (0.51) | HRH3DRD4DRD2DRD3ALDH3A1 | |
| SCHEMBL5536818 | 0.86 | DRD4 (0.49) | DRD4DRD2DRD3ALDH3A1KCNH2 | |
| SCHEMBL30514014 | 0.84 | HRH3 (0.61) | HRH3DRD4DRD2DRD3ALDH3A1 | |
| SCHEMBL11815991 | 0.84 | HRH3 (0.61) | HRH3DRD4DRD2DRD3ALDH3A1 | |
| SCHEMBL9770302 | 0.82 | ALDH3A1 (0.62) | HRH3DRD4DRD2DRD3ALDH3A1 | |
| SCHEMBL9441058 | 0.81 | HRH3 (0.49) | HRH3DRD4DRD2DRD3ALDH3A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992001447-A1 | 2-CYCLOPROPYLACETIC ACID DERIVATIVES | SANDOZ LTD. (CH) | 1992-02-06 | — | — | WO | disclosed |