Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 5/20 | 0.53 |
| ▸ | CNR1 | P21554 | 1/20 | 0.53 |
| ▸ | CNR2 | P34972 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | NAAA | Q02083 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6897022 | 0.88 | FAAH (0.65) | FAAHCNR1CNR2LMNANAAA | |
| SCHEMBL6339017 | 0.88 | FAAH (0.65) | FAAHCNR1CNR2LMNANAAA | |
| SCHEMBL28763670 | 0.88 | FAAH (0.65) | FAAHCNR1CNR2LMNANAAA | |
| SCHEMBL9447664 | 0.88 | FAAH (0.65) | FAAHCNR1CNR2LMNANAAA | |
| SCHEMBL8994200 | 0.88 | FAAH (0.65) | FAAHCNR1CNR2LMNANAAA | |
| SCHEMBL6906595 | 0.88 | FAAH (0.65) | FAAHCNR1CNR2LMNANAAA | |
| SCHEMBL13126847 | 0.88 | FAAH (0.65) | FAAHCNR1CNR2LMNANAAA | |
| SCHEMBL4805826 | 0.88 | FAAH (0.65) | FAAHCNR1CNR2LMNANAAA | |
| SCHEMBL28213215 | 0.86 | FAAH (0.62) | FAAHCNR1CNR2LMNANAAA | |
| SCHEMBL18157282 | 0.83 | NAAA (0.46) | FAAHCNR1CNR2LMNANAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5122519-A | Tetracyclines in solvent, gelling vehicle | AMERICAN CYANAMID COMPANY (US) | 1992-06-16 | — | — | US | claimed |
| EP-0410099-A1 | Stable, cosmetically acceptable topical gel formulation and method of treatment for acne | AMERICAN CYANAMID COMPANY (US) | 1991-01-30 | — | — | EP | claimed |
| US-5122519-A | Tetracyclines in solvent, gelling vehicle | AMERICAN CYANAMID COMPANY (US) | 1992-06-16 | — | — | US | disclosed |
| EP-0410099-A1 | Stable, cosmetically acceptable topical gel formulation and method of treatment for acne | AMERICAN CYANAMID COMPANY (US) | 1991-01-30 | — | — | EP | disclosed |