Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | TNKS | O95271 | 2/20 | 0.48 |
| ▸ | TNKS2 | Q9H2K2 | 2/20 | 0.48 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.48 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GUSB | P08236 | 2/20 | 0.40 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7517964 | 0.75 | ALDH1A1 (0.42) | RECQLTNKSTNKS2PARP2PDGFRB | |
| SCHEMBL9696096 | 0.74 | BTK (0.40) | TNKSTNKS2HPGDPOLBNPC1 | |
| SCHEMBL4147456 | 0.74 | MAPT (0.46) | TNKSTNKS2ADORA2AHPGDADORA1 | |
| SCHEMBL17280154 | 0.73 | PDGFRB (0.45) | RECQLPDGFRBHTTHPGDPDGFRA | |
| SCHEMBL1660430 | 0.73 | KDM4E (0.60) | PDGFRBHTTADORA2AHPGDGUSB | |
| SCHEMBL1683758 | 0.72 | CNR2 (0.52) | TNKSTNKS2PARP2ADORA3ADORA2A | |
| SCHEMBL4423277 | 0.71 | TUBB4A (0.49) | PDGFRBHPGDMAPTKDM4EMEN1 | |
| SCHEMBL24392021 | 0.71 | PDE3B (0.63) | RECQLTNKSTNKS2PARP2HTT | |
| SCHEMBL29588668 | 0.71 | PDE3B (0.63) | RECQLTNKSTNKS2PARP2HTT | |
| SCHEMBL15775406 | 0.71 | TNKS (0.63) | RECQLTNKSTNKS2PARP2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992005159-A1 | 2-PHENYL-PYRIMIDINES, PROCESS FOR PRODUCING THE SAME, AGENTS CONTAINING THE SAME AND THEIR USE AS FUNGICIDES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-04-02 | — | — | WO | disclosed |