Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A3 | P43003 | 1/20 | 0.37 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.37 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698660 | 0.74 | SLC7A5 (0.37) | SLC1A3SLC1A2SLC1A1SLC7A5 | |
| SCHEMBL9696173 | 0.68 | SLC1A3 (0.42) | SLC1A3SLC1A2SLC1A1SLC7A5 | |
| SCHEMBL1165442 | 0.68 | — | — | |
| SCHEMBL9697182 | 0.67 | GABRR1 (0.36) | — | |
| SCHEMBL9329975 | 0.65 | SLC7A5 (0.48) | SLC1A3SLC1A2SLC1A1SLC7A5 | |
| SCHEMBL9329977 | 0.65 | SLC7A5 (0.48) | SLC1A3SLC1A2SLC1A1SLC7A5 | |
| SCHEMBL7706171 | 0.65 | — | — | |
| Alanine SCHEMBL28847741 | 0.64 | SLC7A5 (0.50) | SLC1A3SLC1A2SLC1A1SLC7A5 | |
| Isopropylamine SCHEMBL10898648 | 0.63 | ALDH1A1 (0.39) | — | |
| Alanine SCHEMBL9329114 | 0.62 | SLC7A5 (0.48) | SLC1A3SLC1A2SLC1A1SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5099063-A | 3-(1-aminoalkylphosphinyl)-(2-substituted)propionic acids | MERCK & CO., INC. (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0266978-A2 | Novel antibacterial agents and potentiators of carbapenem antibiotics | MERCK & CO. INC. (US) | 1988-05-11 | — | — | EP | disclosed |