Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 3/20 | 0.44 |
| ▸ | SLC1A2 | P43004 | 3/20 | 0.44 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.44 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.39 |
| ▸ | LAP3 | P28838 | 8/20 | 0.36 |
| ▸ | ANPEP | P15144 | 3/20 | 0.36 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.34 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.34 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9329975 | 1.00 | SLC7A5 (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL19411426 | 0.76 | SLC7A5 (0.58) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL2412183 | 0.75 | RNPEP (0.55) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| Leucine SCHEMBL1191424 | 0.72 | SLC7A5 (0.82) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| Leucine SCHEMBL1191429 | 0.72 | SLC7A5 (0.82) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL2717757 | 0.71 | SLC1A3 (0.62) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL5037193 | 0.69 | — | — | |
| SCHEMBL7453161 | 0.69 | RNPEP (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL7407601 | 0.69 | RNPEP (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP | |
| SCHEMBL27731259 | 0.69 | RNPEP (0.48) | SLC7A5SLC1A3SLC1A2SLC1A1RNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5304549-A | Control or prevention of degenerative joint diseases | HOFFMANN-LA ROCHE INC. (US) | 1994-04-19 | — | — | US | disclosed |
| EP-0497192-A2 | Amino acid derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1992-08-05 | — | — | EP | disclosed |