SCHEMBL969641

SCHEMBL969641

CCN(C(N)=O)C(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 1/20 0.35
LMNA P02545 1/20 0.31
HSD17B10 Q99714 1/20 0.31
ALOX15 P16050 1/20 0.31
DPP4 P27487 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL968380 0.81 SLC6A2 (0.33) SLC6A2
SCHEMBL2828870 0.80 CA12 (0.34) LMNAHSD17B10
SCHEMBL2828416 0.79
SCHEMBL967486 0.77 MLYCD (0.31)
SCHEMBL968381 0.76 MEN1 (0.37) SLC6A2LMNA
SCHEMBL497973 0.76 CHRM1 (0.33) SLC6A2
SCHEMBL2829823 0.75 MAPT (0.32)
SCHEMBL27477241 0.75 CA1 (0.36)
SCHEMBL10911761 0.75 DPP4 (0.37) DPP4
SCHEMBL969639 0.74 SLC6A2 (0.32) SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107108851-B Dynamic urea linkage of polymers 伊利诺伊大学董事会 2021-01-08 CN disclosed
US-10822448-B2 Dynamic urea bonds with fast hydrolytic kinetics for polymers THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2020-11-03 US disclosed
US-20200239622-A1 DYNAMIC UREA BONDS FOR POLYMERS NATIONAL SCIENCE FOUNDATION 2020-07-30 US disclosed
US-10428171-B2 Cyclic dynamic polyureas for polymeric urea processing THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2019-10-01 US disclosed
US-20190092898-A1 DYNAMIC UREA BONDS WITH FAST HYDROLYTIC KINETICS FOR POLYMERS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2019-03-28 US disclosed
US-10000608-B2 Dynamic urea bonds for reversible and self-healing polymers THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2018-06-19 US disclosed
US-10000608-B2 Dynamic urea bonds for reversible and self-healing polymers THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2018-06-19 US disclosed
US-20180009933-A1 CYCLIC DYNAMIC POLYUREAS FOR POLYMERIC UREA PROCESSING THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2018-01-11 US disclosed
US-20170327627-A1 DYNAMIC UREA BONDS FOR POLYMERS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS 2017-11-16 US disclosed
WO-2017155958-A1 DYNAMIC UREA BONDS WITH FAST HYDROLYTIC KINETICS FOR POLYMERS THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS (US) 2017-09-14 WO disclosed
US-7511038-B2 Pyridazin-3(2H)-one derivatives and their use as PDE4 inhibitors LABORATORIOS ALMIRALL S.A. (ES) 2009-03-31 US disclosed
EP-1575926-B1 NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES ALMIRALL LAB (ES) 2008-03-05 EP disclosed
EP-1781621-A1 PYRIDAZIN-3(2H)-ONE DERIVATIVES AND THEIR USE AS PDE4 INHIBITORS Laboratorios Almirall, S.A. (ES) 2007-05-09 EP disclosed
EP-1682519-A1 PYRIDAZIN-3(2H)-ONE DERIVATIVES AND THEIR USE AS PDE4 INHIBITORS Almirall Prodesfarma, S.A. (ES) 2006-07-26 EP disclosed
WO-2005123693-A1 PYRIDAZIN-3(2H)-ONE DERIVATIVES AND THEIR USE AS PDE4 INHIBITORS LABORATORIOS ALMIRALL, S.A. (ES) 2005-12-29 WO disclosed
EP-1575926-A1 NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES Almirall Prodesfarma, S.A. (ES) 2005-09-21 EP disclosed
WO-2005049581-A1 PYRIDAZIN-3 (2H) -ONE DERIVATIVES AND THEIR USE AS PDE4 INHIBITORS ALMIRALL PRODESFARMA, S.A. (ES) 2005-06-02 WO disclosed
WO-2004058729-A1 NEW PYRIDAZIN-3(2H)-ONE DERIVATIVES ALMIRALL PRODESFARMA SA (ES) 2004-07-15 WO disclosed
US-6028033-A FOR CONTROLLING UNDESIRED VEGETATION BASF AKTIENGESELLSCHAFT (DE) 2000-02-22 US disclosed
WO-1996037471-A1 N-AMINOPYRIDONE DERIVATIVES AND THEIR USE AS HERBICIDES BASF AKTIENGESELLSCHAFT (DE) 1996-11-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10822448-B2 Dynamic urea bonds with fast hydrolytic kinetics for polymers PUF60, PCNA, UMPS SLC6A2 2560/4885LMNA 2599/4885HSD17B10 3421/4885
US-20170327627-A1 DYNAMIC UREA BONDS FOR POLYMERS KDM4D, KDM4A, UMPS SLC6A2 1911/4885LMNA 3264/4885HSD17B10 4101/4885
US-20190092898-A1 DYNAMIC UREA BONDS WITH FAST HYDROLYTIC KINETICS FOR POLYMERS PUF60, PCNA, UMPS SLC6A2 2560/4885LMNA 2599/4885HSD17B10 3421/4885
US-20200239622-A1 DYNAMIC UREA BONDS FOR POLYMERS KDM4D, KDM4A, UMPS SLC6A2 1911/4885LMNA 3264/4885HSD17B10 4101/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.