Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.46 |
| ▸ | HTR2C | P28335 | 3/20 | 0.46 |
| ▸ | HTR7 | P34969 | 2/20 | 0.46 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.41 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | TACR2 | P21452 | 1/20 | 0.40 |
| ▸ | TACR1 | P25103 | 1/20 | 0.40 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.40 |
| ▸ | PRCP | P42785 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697219 | 0.87 | HTR2A (0.44) | HTR2AHTR2CHTR7KCNH2NR4A2 | |
| SCHEMBL9696669 | 0.85 | HRH1 (0.55) | HTR2AHTR2CHTR7KCNH2SSTR5 | |
| SCHEMBL9696761 | 0.85 | CYP2D6 (0.43) | HTR2AHTR2CHTR7KCNH2HRH1 | |
| SCHEMBL9697155 | 0.84 | HTR2A (0.41) | HTR2AHTR2CHTR7KCNH2NR4A2 | |
| SCHEMBL9697130 | 0.77 | KCNH2 (0.48) | HTR2AHTR2CHTR7KCNH2NR4A2 | |
| SCHEMBL9695586 | 0.76 | KCNH2 (0.51) | HTR2AHTR2CHTR7KCNH2NR4A2 | |
| SCHEMBL9445676 | 0.75 | HRH1 (0.68) | HTR2AHTR2CHTR7KCNH2NR4A2 | |
| SCHEMBL9695625 | 0.75 | HRH1 (0.48) | HTR2AHTR2CKCNH2HRH1 | |
| SCHEMBL9537288 | 0.74 | SSTR5 (0.53) | HTR2AHTR2CHTR7KCNH2NR4A2 | |
| SCHEMBL9258632 | 0.73 | HRH1 (0.56) | KCNH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006086-A1 | NOVEL 4-PIPERIDINYLCARBONYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-04-16 | — | — | WO | disclosed |