Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.39 |
| ▸ | SSTR5 | P35346 | 2/20 | 0.39 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.39 |
| ▸ | HTR3B | O95264 | 1/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | HTR3A | P46098 | 1/20 | 0.39 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.39 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697130 | 0.90 | KCNH2 (0.48) | HTR2AHTR2CHTR7KCNH2NR4A2 | |
| SCHEMBL9697219 | 0.87 | HTR2A (0.44) | HTR2AHTR2CHTR7KCNH2NR4A2 | |
| SCHEMBL9696761 | 0.85 | CYP2D6 (0.43) | HTR2AHTR2CHTR7KCNH2HTR3E | |
| SCHEMBL9696476 | 0.84 | HTR2A (0.46) | HTR2AHTR2CHTR7KCNH2NR4A2 | |
| SCHEMBL9696669 | 0.82 | HRH1 (0.55) | HTR2AHTR2CHTR7KCNH2SSTR5 | |
| SCHEMBL10551207 | 0.81 | SSTR5 (0.58) | HTR2AHTR2CHTR7KCNH2NR4A2 | |
| SCHEMBL9537882 | 0.81 | SLC6A9 (0.41) | HTR2CKCNH2NR4A2SSTR5HTR3E | |
| Oxalic Acid SCHEMBL9538518 | 0.79 | GRIN2B (0.41) | SSTR5OPRK1TP53 | |
| Oxalic Acid SCHEMBL9538513 | 0.79 | GRIN2B (0.41) | SSTR5OPRK1TP53 | |
| Oxalic Acid SCHEMBL10802671 | 0.79 | GRIN2B (0.41) | SSTR5OPRK1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006086-A1 | NOVEL 4-PIPERIDINYLCARBONYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-04-16 | — | — | WO | disclosed |