Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 17/20 | 0.68 |
| ▸ | PPARA | Q07869 | 16/20 | 0.68 |
| ▸ | ALOX5 | P09917 | 14/20 | 0.68 |
| ▸ | PTGES | O14684 | 11/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858491 | 0.86 | PPARG (0.75) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9613827 | 0.85 | PPARG (0.73) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9613945 | 0.81 | ALDH1A1 (0.50) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9696784 | 0.81 | ALDH1A1 (0.50) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9613848 | 0.80 | PPARG (0.81) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9613840 | 0.78 | PPARG (0.59) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9614172 | 0.77 | PPARG (0.47) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9858468 | 0.76 | PPARG (0.74) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9857889 | 0.76 | PPARG (0.74) | PPARGPPARAALOX5PTGESALDH1A1 | |
| SCHEMBL9614203 | 0.75 | PPARG (0.72) | PPARGPPARAALOX5PTGESALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507238-A1 | Optically active carboxylic acids and medicinal preparations containing them | Roche Diagnostics GmbH (DE) | 1992-10-07 | — | — | EP | disclosed |