Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.72 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.72 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.72 |
| ▸ | LMNA | P02545 | 3/20 | 0.71 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | NPC1 | O15118 | 2/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9166162 | 0.96 | TDP1 (0.72) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL21924208 | 0.95 | KMT2A (0.66) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL6282770 | 0.94 | KMT2A (0.81) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL18736538 | 0.90 | TDP1 (0.64) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL9266925 | 0.89 | KMT2A (0.72) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL312211 | 0.89 | KMT2A (0.72) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL14166129 | 0.89 | KMT2A (0.62) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL22498785 | 0.89 | RAB9A (0.67) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL6655185 | 0.89 | TDP1 (0.62) | TDP1KMT2ASLC6A2SLC6A3LMNA | |
| SCHEMBL312910 | 0.87 | TDP1 (0.81) | TDP1KMT2ASLC6A2SLC6A3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992001476-A1 | NOVEL DRUG DELIVERY SYSTEMS FOR PROTEINS AND PEPTIDES USING ALBUMIN AS A CARRIER MOLECULE | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 1992-02-06 | — | — | WO | disclosed |