Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.36 |
| ▸ | DRD2 | P14416 | 6/20 | 0.34 |
| ▸ | HTR1A | P08908 | 6/20 | 0.34 |
| ▸ | HTR2A | P28223 | 6/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | DRD4 | P21917 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9535132 | 0.85 | SLC6A9 (0.43) | DRD2HTR1AHTR2APOLBALDH1A1 | |
| SCHEMBL9695634 | 0.78 | HPGD (0.42) | CACNA2D1HTR1APOLBALDH1A1TSHR | |
| SCHEMBL9537833 | 0.76 | ALDH1A1 (0.39) | DRD2HTR1AHTR2APOLBALDH1A1 | |
| SCHEMBL9537922 | 0.72 | ALDH1A1 (0.38) | DRD2HTR1AHTR2APOLBALDH1A1 | |
| SCHEMBL6523129 | 0.72 | HTR2A (0.53) | DRD2HTR1AHTR2AALDH1A1TSHR | |
| SCHEMBL6523131 | 0.72 | HTR2A (0.53) | DRD2HTR1AHTR2AALDH1A1TSHR | |
| SCHEMBL6523137 | 0.72 | HTR2A (0.53) | DRD2HTR1AHTR2AALDH1A1TSHR | |
| Barmastine SCHEMBL30712053 | 0.70 | KDM4E (0.45) | DRD2HTR1AHTR2APOLBALDH1A1 | |
| Barmastine SCHEMBL141926 | 0.70 | KDM4E (0.45) | DRD2HTR1AHTR2APOLBALDH1A1 | |
| SCHEMBL9695625 | 0.70 | HRH1 (0.48) | HTR2AALDH1A1TSHRLMNAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992006086-A1 | NOVEL 4-PIPERIDINYLCARBONYL DERIVATIVES | JANSSEN PHARMACEUTICA N.V. (BE) | 1992-04-16 | — | — | WO | disclosed |