Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.77 |
| ▸ | HTR7 | P34969 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.57 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | DRD2 | P14416 | 1/20 | 0.55 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.52 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.52 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.51 |
| ▸ | EGFR | P00533 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491320 | 0.87 | MAPKAPK2 (1.00) | MAPKAPK2HTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL12395388 | 0.87 | MAPKAPK2 (1.00) | MAPKAPK2HTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL21465236 | 0.87 | MAPKAPK2 (1.00) | MAPKAPK2HTR7CYP3A4CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL10406908 | 0.86 | MAPKAPK2 (0.97) | MAPKAPK2HTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL28439443 | 0.86 | MAPKAPK2 (0.77) | MAPKAPK2HTR7CYP3A4CYP2D6CYP2C19 | |
| Acetone SCHEMBL27932467 | 0.85 | MAPKAPK2 (0.68) | MAPKAPK2HTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL1491406 | 0.85 | MAPKAPK2 (0.71) | MAPKAPK2HTR7CYP3A4CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL28201946 | 0.84 | MAPKAPK2 (0.70) | MAPKAPK2HTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL28918986 | 0.82 | MAPKAPK2 (0.71) | MAPKAPK2HTR7CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7267623 | 0.82 | MAPKAPK2 (0.67) | MAPKAPK2HTR7CYP3A4CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5169852-A | Anorexigenic agents | NEUREX CORPORATION (US) | 1992-12-08 | — | — | US | disclosed |