Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPKAPK2 | P49137 | 7/20 | 0.68 |
| ▸ | HTR7 | P34969 | 3/20 | 0.53 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 3/20 | 0.51 |
| ▸ | EGFR | P00533 | 3/20 | 0.51 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1491406 | 0.97 | MAPKAPK2 (0.71) | MAPKAPK2HTR7MAPKAPK5KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL28201946 | 0.96 | MAPKAPK2 (0.70) | MAPKAPK2HTR7MAPKAPK5KDM4EHSD17B10 | |
| SCHEMBL9696707 | 0.85 | MAPKAPK2 (0.77) | MAPKAPK2HTR7MAPKAPK5CYP2D6CYP2C19 | |
| SCHEMBL273473 | 0.84 | MAPKAPK2 (0.67) | MAPKAPK2HTR7MAPKAPK5KDM4EHSD17B10 | |
| SCHEMBL29808213 | 0.84 | MAPKAPK2 (0.67) | MAPKAPK2HTR7MAPKAPK5CYP2D6CYP2C19 | |
| SCHEMBL10489357 | 0.84 | MAPKAPK2 (0.67) | MAPKAPK2HTR7MAPKAPK5CYP2D6CYP2C19 | |
| SCHEMBL10481507 | 0.84 | MAPKAPK2 (0.67) | MAPKAPK2HTR7MAPKAPK5KDM4EHSD17B10 | |
| SCHEMBL14924843 | 0.81 | MAPKAPK2 (0.77) | MAPKAPK2MAPKAPK5 | |
| SCHEMBL1491320 | 0.81 | MAPKAPK2 (1.00) | MAPKAPK2HTR7MAPKAPK5CYP2D6CYP2C19 | |
| SCHEMBL21465236 | 0.81 | MAPKAPK2 (1.00) | MAPKAPK2HTR7MAPKAPK5CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103450340-B | The antineoplastic oligopeptide that heterocyclic carboxylic acid is modified, its synthesis, antitumor action and application | Capital Medical University (CN) | 2015-08-05 | — | — | CN | claimed |
| CN-103450340-A | Heterocyclic carboxylic acid-modified anti-tumor oligopeptides and their synthesis, anti-tumor effects and application | UNIV CAPITAL MEDICAL SCIENCES | 2013-12-18 | — | — | CN | claimed |
| CN-103450340-B | The antineoplastic oligopeptide that heterocyclic carboxylic acid is modified, its synthesis, antitumor action and application | Capital Medical University (CN) | 2015-08-05 | — | — | CN | disclosed |
| CN-103450340-A | Heterocyclic carboxylic acid-modified anti-tumor oligopeptides and their synthesis, anti-tumor effects and application | UNIV CAPITAL MEDICAL SCIENCES | 2013-12-18 | — | — | CN | disclosed |