Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.34 |
| ▸ | JAK3 | P52333 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7014623 | 0.80 | — | — | |
| SCHEMBL6963400 | 0.80 | — | — | |
| SCHEMBL7014622 | 0.80 | — | — | |
| SCHEMBL28035994 | 0.79 | GRIN2B (0.40) | GRIN2BGRIN2CHPGDUSP2SMN1; SMN2 | |
| SCHEMBL15425361 | 0.77 | GRIN2B (0.37) | GRIN2BGRIN2CHPGDNR1H2NR1H3 | |
| SCHEMBL475482 | 0.76 | GRIN2B (0.44) | GRIN2BGRIN2CHPGDUSP2SMN1; SMN2 | |
| SCHEMBL932957 | 0.74 | GRIN2B (0.43) | GRIN2BGRIN2CHPGDUSP2SMN1; SMN2 | |
| SCHEMBL4730578 | 0.73 | GRIN2B (0.42) | GRIN2BGRIN2CHPGDUSP2SMN1; SMN2 | |
| SCHEMBL8528362 | 0.73 | GRIN2B (0.45) | GRIN2BGRIN2CHPGDNR1H2NR1H3 | |
| SCHEMBL28721452 | 0.73 | GRIN2B (0.42) | GRIN2BGRIN2CHPGDUSP2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |