Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | CCR3 | P51677 | 7/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9529299 | 0.99 | KCNH2 (0.51) | KCNH2SLC6A2SLC6A4SLC6A3CCR3 | |
| SCHEMBL9699172 | 0.83 | CCR3 (0.43) | SLC6A2SLC6A4SLC6A3CCR3CYP2D6 | |
| SCHEMBL23686896 | 0.82 | POLB (0.51) | KCNH2SLC6A2SLC6A4SLC6A3CYP2D6 | |
| Hydrochloric Acid SCHEMBL9527656 | 0.82 | CCR3 (0.42) | SLC6A2SLC6A4SLC6A3CCR3CYP2D6 | |
| Hydrochloric Acid SCHEMBL9527122 | 0.82 | SIGMAR1 (0.51) | KCNH2CCR3 | |
| Fluorobenzene SCHEMBL27358863 | 0.81 | CARM1 (0.49) | KCNH2SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23686785 | 0.79 | HRH3 (0.55) | KCNH2POLBRAB9ASMN1; SMN2LMNA | |
| Oxalic Acid SCHEMBL9528351 | 0.77 | CHRNB4 (0.47) | CCR3CYP2D6 | |
| SCHEMBL23686820 | 0.77 | HDAC1 (0.48) | KCNH2SLC6A2SLC6A3MEN1KMT2A | |
| SCHEMBL23686823 | 0.77 | HDAC1 (0.48) | KCNH2SLC6A2SLC6A3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002501-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | disclosed |