Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 8/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | BACE1 | P56817 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9527656 | 0.99 | CCR3 (0.42) | CCR3CYP2D6HTR2ASLC6A2SLC6A4 | |
| SCHEMBL9696845 | 0.83 | KCNH2 (0.52) | CCR3CYP2D6HTR2ASLC6A2SLC6A4 | |
| Hydrochloric Acid SCHEMBL9529299 | 0.82 | KCNH2 (0.51) | CCR3CYP2D6HTR2ASLC6A2SLC6A4 | |
| SCHEMBL9530101 | 0.82 | CCR2 (0.48) | — | |
| Hydrochloric Acid SCHEMBL9532042 | 0.81 | CCR2 (0.47) | — | |
| Fluorobenzene SCHEMBL27358863 | 0.81 | CARM1 (0.49) | SLC6A2SLC6A4SLC6A3BCHE | |
| SCHEMBL9527998 | 0.78 | MEN1 (0.51) | LMNAMEN1KMT2A | |
| Oxalic Acid SCHEMBL9528825 | 0.74 | KDM4E (0.53) | LMNAPOLB | |
| 1,2-Dichlorobenzene SCHEMBL27524525 | 0.72 | CARM1 (0.47) | BCHELMNA | |
| Fluorobenzene SCHEMBL27375567 | 0.72 | CHRNB4 (0.52) | BCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002501-A1 | 3-SUBSTITUTED PIPERIDINE DERIVATIVES | SMITHKLINE & FRENCH LABORATORIES LIMITED (GB) | 1992-02-20 | — | — | WO | disclosed |