Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MGAM | O43451 | 1/20 | 0.39 |
| ▸ | SI | P14410 | 1/20 | 0.39 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2422852 | 0.89 | KMT2A (0.42) | KMT2AL3MBTL1GAAMGAMSI | |
| Hydrochloric Acid SCHEMBL8126733 | 0.81 | KMT2A (0.38) | KMT2AL3MBTL1GAAMGAMSI | |
| SCHEMBL22777434 | 0.75 | TSHR (0.42) | KMT2AL3MBTL1GAAMGAMSI | |
| SCHEMBL22784325 | 0.72 | GRM1 (0.38) | KMT2AALDH1A1TSHRLMNAPOLB | |
| SCHEMBL592258 | 0.70 | OPRM1 (0.40) | — | |
| SCHEMBL31618421 | 0.69 | LMNA (0.50) | KMT2AL3MBTL1GAAMGAMSI | |
| Bromide SCHEMBL6628170 | 0.69 | OPRM1 (0.39) | — | |
| SCHEMBL597365 | 0.69 | KMT2A (0.51) | KMT2AL3MBTL1GAAMGAMSI | |
| SCHEMBL16276877 | 0.69 | GAA (0.48) | KMT2AL3MBTL1GAAMGAMSI | |
| SCHEMBL380983 | 0.69 | GAA (0.48) | KMT2AL3MBTL1GAAMGAMSI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091397-A | Cognition activators | BEECHAM GROUP P.L.C. (GB) | 1992-02-25 | — | — | US | disclosed |
| EP-0363085-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-04-11 | — | — | EP | disclosed |