Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 15/20 | 0.64 |
| ▸ | PTGES | O14684 | 8/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.45 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697037 | 0.85 | GAA (0.65) | ALOX5PTGESMAPTKDM4EMEN1 | |
| SCHEMBL9698103 | 0.84 | ALOX5 (0.52) | ALOX5PTGESMAPTKDM4EMEN1 | |
| SCHEMBL9698079 | 0.80 | ALOX5 (0.53) | ALOX5PTGESMAPTKDM4EMEN1 | |
| SCHEMBL9695875 | 0.80 | GAA (0.47) | ALOX5PTGESMAPTKDM4EMEN1 | |
| SCHEMBL9696910 | 0.79 | ADORA2B (0.49) | ALOX5PTGESMAPTKDM4EMEN1 | |
| SCHEMBL9697631 | 0.78 | KDM4E (0.50) | ALOX5PTGESMAPTKDM4EMEN1 | |
| SCHEMBL9696908 | 0.76 | ALOX5 (0.56) | ALOX5PTGESMAPTKDM4EMEN1 | |
| SCHEMBL9697639 | 0.76 | NR1H2 (0.55) | ALOX5MAPTKDM4EMEN1ALDH1A1 | |
| SCHEMBL6295738 | 0.73 | ALOX5 (0.60) | ALOX5PTGESMAPTKDM4EMEN1 | |
| SCHEMBL9697799 | 0.73 | NR1H2 (0.51) | ALOX5MAPTKDM4EMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992003419-A1 | ISOCARBOSTIRYL COMPOUNDS AND ANTITUMOR USE THEREOF | SYNPHAR LABORATORIES, INC. (CA) | 1992-03-05 | — | — | WO | disclosed |