Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GFER | P55789 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697536 | 0.83 | SMN1; SMN2 (0.44) | HTTALDH1A1KDM4EHPGDKMT2A | |
| SCHEMBL9697103 | 0.75 | HTT (0.48) | HTTCYP1A2CYP2D6ALDH1A1KDM4E | |
| SCHEMBL12930508 | 0.74 | HTT (0.57) | HTTCYP1A2CYP2D6ALDH1A1KDM4E | |
| SCHEMBL230862 | 0.70 | ALDH1A1 (0.51) | HTTCYP1A2CYP2D6ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL9697011 | 0.70 | NOD2 (0.42) | CYP1A2CYP2D6ALDH1A1KDM4EKMT2A | |
| Hydrochloric Acid SCHEMBL9753091 | 0.69 | NOD2 (0.39) | HTTCYP2D6ALDH1A1KDM4EKMT2A | |
| SCHEMBL228862 | 0.69 | CYP1A2 (0.47) | HTTCYP1A2CYP2D6ALDH1A1KDM4E | |
| Dimethylamine SCHEMBL6930952 | 0.68 | CYP1A2 (0.90) | HTTCYP1A2CYP2D6ALDH1A1KDM4E | |
| SCHEMBL20550090 | 0.68 | ALDH1A1 (0.47) | HTTCYP1A2CYP2D6ALDH1A1KDM4E | |
| SCHEMBL230641 | 0.68 | ALDH1A1 (0.70) | HTTCYP1A2CYP2D6ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5149700-A | Antiarrhythmic agent | AMERICAN HOME PRODUCTS CORPORATION (US) | 1992-09-22 | — | — | US | disclosed |
| WO-1991018904-A1 | SUBSTITUTED ARYLSULFONAMIDES AND BENZAMIDES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1991-12-12 | — | — | WO | disclosed |