Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 4/20 | 0.77 |
| ▸ | ANPEP | P15144 | 4/20 | 0.77 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.53 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.53 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.46 |
| ▸ | IL1RN | P18510 | 2/20 | 0.46 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.46 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9697359 | 0.85 | ANPEP (0.56) | LAP3ANPEPSLC1A3SLC1A2ERAP2 | |
| SCHEMBL9696270 | 0.81 | ANPEP (0.53) | LAP3ANPEPERAP2 | |
| SCHEMBL9696208 | 0.81 | FOLH1 (0.60) | LAP3ANPEP | |
| SCHEMBL9696300 | 0.81 | ANPEP (0.53) | LAP3ANPEPERAP2 | |
| SCHEMBL27431060 | 0.80 | LAP3 (0.65) | LAP3ANPEPSLC1A3SLC1A2ERAP1 | |
| SCHEMBL9715079 | 0.80 | CHRM1 (0.52) | LAP3ANPEPSLC1A3SLC1A2 | |
| SCHEMBL7605053 | 0.79 | FOLH1 (0.62) | LAP3ANPEP | |
| SCHEMBL9697381 | 0.77 | SLC1A2 (0.53) | LAP3ANPEPSLC1A3SLC1A2 | |
| SCHEMBL9696243 | 0.76 | ANPEP (0.46) | LAP3ANPEP | |
| SCHEMBL9797611 | 0.76 | SLC7A5 (0.46) | LAP3ANPEPSLC1A3SLC1A2SLC7A5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143908-A | Carboxylic acids containing amino and phosphinyl groups | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| US-5099063-A | 3-(1-aminoalkylphosphinyl)-(2-substituted)propionic acids | MERCK & CO., INC. (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0266978-A2 | Novel antibacterial agents and potentiators of carbapenem antibiotics | MERCK & CO. INC. (US) | 1988-05-11 | — | — | EP | disclosed |
| US-4715994-A | PHOSPHINIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1987-12-29 | — | — | US | disclosed |