Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 4/20 | 0.56 |
| ▸ | LAP3 | P28838 | 1/20 | 0.56 |
| ▸ | GCLC | P48506 | 1/20 | 0.54 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9715079 | 0.87 | CHRM1 (0.52) | ANPEPLAP3GCLCSLC1A3SLC1A2 | |
| SCHEMBL9696300 | 0.85 | ANPEP (0.53) | ANPEPLAP3GCLCMMEERAP2 | |
| SCHEMBL9696270 | 0.85 | ANPEP (0.53) | ANPEPLAP3GCLCMMEERAP2 | |
| SCHEMBL9696208 | 0.85 | FOLH1 (0.60) | ANPEPLAP3GCLCMME | |
| SCHEMBL9697243 | 0.85 | LAP3 (0.77) | ANPEPLAP3SLC1A3SLC1A2ERAP2 | |
| SCHEMBL9646355 | 0.84 | ANPEP (0.61) | ANPEPLAP3GCLCSLC1A3SLC1A2 | |
| SCHEMBL9697381 | 0.84 | SLC1A2 (0.53) | ANPEPLAP3GCLCSLC1A3SLC1A2 | |
| SCHEMBL7605053 | 0.82 | FOLH1 (0.62) | ANPEPLAP3 | |
| SCHEMBL9697329 | 0.81 | GRIK1 (0.55) | ANPEPLAP3SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL9797611 | 0.79 | SLC7A5 (0.46) | ANPEPLAP3GCLCSLC1A3SLC1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5143908-A | Carboxylic acids containing amino and phosphinyl groups | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | claimed |
| US-5099063-A | 3-(1-aminoalkylphosphinyl)-(2-substituted)propionic acids | MERCK & CO., INC. (US) | 1992-03-24 | — | — | US | claimed |
| EP-0266978-A2 | Novel antibacterial agents and potentiators of carbapenem antibiotics | MERCK & CO. INC. (US) | 1988-05-11 | — | — | EP | claimed |
| US-5143908-A | Carboxylic acids containing amino and phosphinyl groups | MERCK & CO., INC. (US) | 1992-09-01 | — | — | US | disclosed |
| US-5099063-A | 3-(1-aminoalkylphosphinyl)-(2-substituted)propionic acids | MERCK & CO., INC. (US) | 1992-03-24 | — | — | US | disclosed |
| EP-0266978-A2 | Novel antibacterial agents and potentiators of carbapenem antibiotics | MERCK & CO. INC. (US) | 1988-05-11 | — | — | EP | disclosed |
| US-4715994-A | PHOSPHINIC ACID DERIVATIVES | MERCK & CO., INC. (US) | 1987-12-29 | — | — | US | disclosed |