Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | MIF | P14174 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.33 |
| ▸ | LTA | P01374 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | RAD51 | Q06609 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | RAD1 | O60671 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6472011 | 0.83 | CYP3A4 (0.54) | CYP3A4TRPA1MAPTNPY1RNPY2R | |
| SCHEMBL6179404 | 0.81 | P2RY6 (0.38) | P2RY6CYP3A4TRPA1MIFMAPT | |
| SCHEMBL10440536 | 0.80 | ALDH2 (0.41) | MAPTTDP1ALDH1A1KDM4EHPGD | |
| SCHEMBL5501717 | 0.76 | P2RY6 (0.48) | P2RY6MIFALDH1A1HSD17B10CA1 | |
| SCHEMBL9697469 | 0.74 | P2RY6 (0.37) | P2RY6CYP3A4TRPA1MIFMAPT | |
| SCHEMBL3036837 | 0.74 | P2RY6 (0.45) | P2RY6CYP3A4TRPA1MIFMAPT | |
| SCHEMBL12180740 | 0.72 | ALDH1A1 (0.46) | MAPTNPY1RNPY2RTDP1ALDH1A1 | |
| SCHEMBL13788937 | 0.72 | ALDH1A1 (0.46) | CYP3A4MIFMAPTTDP1ALDH1A1 | |
| SCHEMBL5796149 | 0.71 | MIF (0.44) | P2RY6CYP3A4MIFMAPTALDH1A1 | |
| SCHEMBL10440375 | 0.71 | NAAA (0.33) | NAAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5134144-A | Insecticides, miticides or nematocides | UNIROYAL CHEMICAL COMPANY, INC. (US) | 1992-07-28 | — | — | US | disclosed |
| WO-1991007393-A1 | PESTICIDAL 3-ARYLURACIL ETHERS AND THIOETHERS | UNIROYAL CHEMICAL LTD./UNIROYAL CHEMICAL LTEE (CA) | 1991-05-30 | — | — | WO | disclosed |