Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | DRD1 | P21728 | 2/20 | 0.38 |
| ▸ | DRD3 | P35462 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696934 | 1.00 | SIGMAR1 (0.43) | SIGMAR1MAPTHDAC11GBA1DRD2 | |
| SCHEMBL14256288 | 0.81 | CCR3 (0.45) | SIGMAR1MAPTHDAC11GBA1 | |
| SCHEMBL9385038 | 0.81 | MAPT (0.44) | SIGMAR1MAPTHDAC11GBA1DRD2 | |
| SCHEMBL20494596 | 0.80 | MAPT (0.43) | SIGMAR1MAPTHDAC11GBA1 | |
| SCHEMBL23326764 | 0.80 | MAPT (0.43) | SIGMAR1MAPTHDAC11GBA1DRD2 | |
| SCHEMBL29504724 | 0.79 | GBA1 (0.45) | SIGMAR1GBA1 | |
| SCHEMBL22506576 | 0.77 | MAPT (0.53) | SIGMAR1MAPTHDAC11GBA1DRD2 | |
| SCHEMBL9962388 | 0.77 | MAPT (0.53) | SIGMAR1MAPTHDAC11GBA1DRD2 | |
| SCHEMBL24938856 | 0.77 | MAPT (0.53) | SIGMAR1MAPTHDAC11GBA1DRD2 | |
| SCHEMBL9802975 | 0.77 | MAPT (0.53) | SIGMAR1MAPTHDAC11GBA1DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |