SCHEMBL969768

SCHEMBL969768

Brc1ccc(-c2cc(-c3ccccc3)c3ccccc3n2)cc1

nearest known ligand 0.65

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACACA Q13085 4/20 0.65
GRM2 Q14416 1/20 0.60
HPGD P15428 3/20 0.56
KDM4E B2RXH2 2/20 0.56
MAPT P10636 2/20 0.56
ALDH1A1 P00352 1/20 0.56
MAPK1 P28482 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
ACHE P22303 2/20 0.54
AGTR1 P30556 1/20 0.53
DHODH Q02127 1/20 0.51
LMNA P02545 3/20 0.51
SMN1; SMN2 Q16637 3/20 0.51
ACP1 P24666 1/20 0.51
BCL2 P10415 1/20 0.51
PDE10A Q9Y233 1/20 0.50
TOP1 P11387 1/20 0.50
TP53 P04637 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29400688 1.00 ACACA (0.65) ACACAGRM2HPGDKDM4EMAPT
SCHEMBL28251703 1.00 ACACA (0.65) ACACAGRM2HPGDKDM4EMAPT
SCHEMBL4594838 0.91 ACACA (0.75) ACACAHPGDKDM4EMAPTALDH1A1
SCHEMBL4607752 0.89 ACACA (0.73) ACACAHPGDKDM4EMAPTALDH1A1
SCHEMBL29399315 0.89 ACACA (0.72) ACACAHPGDKDM4EMAPTALDH1A1
SCHEMBL1042853 0.89 ACACA (0.72) ACACAHPGDKDM4EMAPTALDH1A1
SCHEMBL18285493 0.88 RXFP1 (0.58) ACACAGRM2HPGDKDM4EMAPT
SCHEMBL16990162 0.87 ACACA (0.70) ACACAHPGDKDM4EMAPTALDH1A1
SCHEMBL9610043 0.86 RXFP1 (0.60) ACACAHPGDKDM4EMAPTALDH1A1
SCHEMBL16203121 0.85 ACACA (0.56) ACACAGRM2HPGDKDM4EMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111825722-B Saturated red-light-emitting fluorenyl benzoquinoline iridium complex 北京印刷学院 2023-06-09 CN claimed
CN-111825722-A Saturated red luminescent fluorenyl benzoquinoline iridium complex 北京印刷学院 2020-10-27 CN claimed
CN-111825722-B Saturated red-light-emitting fluorenyl benzoquinoline iridium complex 北京印刷学院 2023-06-09 CN disclosed
EP-3752512-B1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2023-03-01 EP disclosed
CN-110724094-B Quinoline compound and synthesis method thereof 陕西科技大学 2022-06-14 CN disclosed
CN-110156673-B Method for preparing quinoline compound by catalysis of zirconocene dichloride 陕西师范大学 2022-02-25 CN disclosed
CN-111825722-A Saturated red luminescent fluorenyl benzoquinoline iridium complex 北京印刷学院 2020-10-27 CN disclosed
CN-110724094-A Quinoline compound and synthesis method thereof 陕西科技大学 2020-01-24 CN disclosed
EP-2730634-B1 NOVEL COMPOUND AND ORGANIC ELECTRONIC DEVICE USING SAME LG CHEMICAL LTD (KR) 2019-10-09 EP disclosed
CN-110156673-A The method that bis cyclopentadienyl zirconium dichloride catalysis prepares quinolines 陕西师范大学 2019-08-23 CN disclosed
WO-2019158453-A1 METAL COMPLEXES MERCK PATENT GMBH (DE) 2019-08-22 WO disclosed
US-20130043460-A1 CARBAZOLE SERIAL COMPOUNDS NATIONAL TSING HUA UNIVERSITY (TW) 2013-02-21 US disclosed
US-20130043460-A1 CARBAZOLE SERIAL COMPOUNDS NATIONAL TSING HUA UNIVERSITY (TW) 2013-02-21 US disclosed
US-20130043460-A1 CARBAZOLE SERIAL COMPOUNDS NATIONAL TSING HUA UNIVERSITY (TW) 2013-02-21 US disclosed
US-7867629-B2 Nitrogenous heterocyclic derivative and organic electroluminescent element employing the same IDEMITSU KOSAN CO., LTD. (JP) 2011-01-11 US disclosed
CN-101407492-A Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO (JP) 2009-04-15 CN disclosed
CN-101219987-A Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO (JP) 2008-07-16 CN disclosed
US-20060154105-A1 Nitrogenous heterocyclic derivative and organic elecrtroluminescent element employing the same IDEMITSU KOSAN CO., LTD. (JP) 2006-07-13 US disclosed
CN-1751024-A Nitrogen-containing heterocyclic derivative and organic electroluminescent element using same IDEMITSU KOSAN CO (JP) 2006-03-22 CN disclosed
EP-1582516-A1 NITROGENOUS HETEROCYCLIC DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT EMPLOYING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2005-10-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130043460-A1 CARBAZOLE SERIAL COMPOUNDS CYCS, CBR3, AADAC ACACA 1319/4885GRM2 4036/4885HPGD 3340/4885
US-20060154105-A1 Nitrogenous heterocyclic derivative and organic elecrtroluminescent element employing the same L1CAM, NOTCH1, NUDC ACACA 3382/4885GRM2 3670/4885HPGD 852/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.