Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ERN1 | O75460 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 3/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696855 | 0.88 | NR1D1 (0.40) | LMNAMAPK1RAB9AERN1NR1D1 | |
| SCHEMBL9698265 | 0.85 | LMNA (0.35) | LMNAMAPK1RAB9ATDP1ERN1 | |
| SCHEMBL9697742 | 0.84 | GAA (0.40) | LMNAMAPK1RAB9AERN1NR1D1 | |
| SCHEMBL9194031 | 0.81 | NR1H2 (0.38) | LMNAMAPK1RAB9ATDP1ERN1 | |
| SCHEMBL31682742 | 0.80 | LMNA (0.33) | LMNAMAPK1RAB9ATDP1ERN1 | |
| SCHEMBL9385294 | 0.80 | LMNA (0.36) | LMNAMAPK1RAB9ATDP1ERN1 | |
| SCHEMBL9699101 | 0.78 | NR1D1 (0.39) | LMNAMAPK1RAB9AERN1TSHR | |
| SCHEMBL6398205 | 0.78 | LMNA (0.38) | LMNAMAPK1RAB9ATDP1ERN1 | |
| SCHEMBL31682800 | 0.76 | LMNA (0.34) | LMNAMAPK1RAB9ATDP1ERN1 | |
| SCHEMBL6398512 | 0.76 | LMNA (0.37) | LMNAMAPK1RAB9ATDP1ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |