Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9696803 | 1.00 | KDM4E (0.37) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9381723 | 0.87 | KDM4E (0.38) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9696813 | 0.86 | KDM4E (0.38) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9699399 | 0.84 | KDM4E (0.37) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9696785 | 0.82 | KDM4E (0.42) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9698231 | 0.80 | ESR1 (0.46) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9697735 | 0.78 | KDM4E (0.40) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9020514 | 0.75 | CACNA1C (0.42) | ESR1 | |
| SCHEMBL9383274 | 0.75 | KDM4E (0.40) | KDM4ELMNAESR1CHRM1SLC6A4 | |
| SCHEMBL9386744 | 0.74 | FAAH (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992002521-A1 | 1-AZABICYCLO[3.2.0]HEPT-2-ENE-2-CARBOXYLIC ACID COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |