Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | ALPG | P10696 | 1/20 | 0.30 |
| ▸ | GFER | P55789 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8467019 | 0.68 | ALDH1A1 (0.37) | ALDH1A1GAA | |
| SCHEMBL4672679 | 0.63 | ALDH1A1 (0.46) | ALDH1A1 | |
| SCHEMBL26135363 | 0.61 | — | — | |
| SCHEMBL22444327 | 0.61 | — | — | |
| SCHEMBL22554805 | 0.61 | — | — | |
| SCHEMBL23043119 | 0.61 | — | — | |
| SCHEMBL23179804 | 0.60 | — | — | |
| SCHEMBL23158212 | 0.60 | CHRNB2 (0.34) | CHRNB2CHRNA4 | |
| SCHEMBL12063279 | 0.60 | CHRNA7 (0.83) | CHRNB2CHRNA7CHRNA4 | |
| SCHEMBL701126 | 0.60 | CHRNA7 (0.83) | CHRNB2CHRNA7CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5091397-A | Cognition activators | BEECHAM GROUP P.L.C. (GB) | 1992-02-25 | — | — | US | disclosed |
| EP-0363085-A2 | Novel compounds | BEECHAM GROUP PLC (GB) | 1990-04-11 | — | — | EP | disclosed |