Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 14/20 | 0.54 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.51 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.51 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.51 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698699 | 0.93 | SOAT1 (0.50) | SOAT1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL9699299 | 0.85 | SOAT1 (0.51) | SOAT1 | |
| SCHEMBL9697944 | 0.84 | SOAT1 (0.47) | SOAT1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL9698728 | 0.84 | SOAT1 (0.47) | SOAT1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL9738813 | 0.81 | SOAT1 (0.65) | SOAT1 | |
| SCHEMBL9699262 | 0.80 | SOAT1 (0.55) | SOAT1 | |
| SCHEMBL9737710 | 0.76 | SOAT1 (0.72) | SOAT1 | |
| SCHEMBL9737115 | 0.76 | SOAT1 (0.72) | SOAT1 | |
| SCHEMBL9698135 | 0.74 | SOAT1 (0.75) | SOAT1 | |
| SCHEMBL9699233 | 0.74 | SOAT1 (0.75) | SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017470-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1992-10-15 | — | — | WO | disclosed |
| EP-0506437-A1 | Imidazoles | RHONE POULENC RORER LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |