Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 4/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.44 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | SOAT2 | O75908 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9698728 | 1.00 | SOAT1 (0.47) | SOAT1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL9698699 | 0.90 | SOAT1 (0.50) | SOAT1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL9697946 | 0.84 | SOAT1 (0.54) | SOAT1MAPK13MAPK12MAPK11MAPK14 | |
| SCHEMBL9738845 | 0.74 | SOAT1 (0.64) | SOAT1 | |
| SCHEMBL9740337 | 0.74 | SOAT1 (0.77) | SOAT1 | |
| SCHEMBL9697999 | 0.72 | SOAT1 (0.63) | SOAT1 | |
| SCHEMBL9698729 | 0.72 | SOAT1 (0.63) | SOAT1 | |
| SCHEMBL9699214 | 0.71 | SOAT1 (0.68) | SOAT1 | |
| SCHEMBL9738395 | 0.71 | SOAT1 (0.86) | SOAT1 | |
| SCHEMBL9737135 | 0.70 | SOAT1 (0.77) | SOAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017470-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1992-10-15 | — | — | WO | disclosed |
| EP-0506437-A1 | Imidazoles | RHONE POULENC RORER LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |