Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.57 |
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 8/20 | 0.49 |
| ▸ | RAB9A | P51151 | 8/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | EGFR | P00533 | 1/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL967418 | 0.93 | SMN1; SMN2 (0.56) | KDM4EMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL969326 | 0.93 | SMN1; SMN2 (0.56) | KDM4EMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL967102 | 0.92 | SMN1; SMN2 (0.59) | KDM4EMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL968069 | 0.92 | SMN1; SMN2 (0.59) | KDM4EMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL968083 | 0.91 | ALDH1A1 (0.54) | KDM4EMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL966642 | 0.87 | SMN1; SMN2 (0.55) | KDM4EMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL966460 | 0.86 | SMN1; SMN2 (0.55) | KDM4EMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL968770 | 0.86 | NPC1 (0.66) | KDM4EMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL30083 | 0.84 | NPC1 (0.62) | KDM4EMAPTALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL12948096 | 0.84 | RAB9A (0.52) | KDM4EMAPTALDH1A1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110009584-A1 | Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-01-13 | — | — | US | disclosed |
| US-20110009584-A1 | Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-01-13 | — | — | US | disclosed |
| US-20110009584-A1 | Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety | GEORGIA TECH RESEARCH CORPORATION (US) | 2011-01-13 | — | — | US | disclosed |
| EP-2234991-A1 | ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY | Georgia Tech Research Corporation (US) | 2010-10-06 | — | — | EP | disclosed |
| WO-2009080797-A1 | ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-07-02 | — | — | WO | disclosed |
| WO-2009080797-A1 | ROMP-POLYMERIZABLE ELECTRON TRANSPORT MATERIALS BASED ON A BIS-OXADIAZOLE MOIETY | GEORGIA TECH RESEARCH CORPORATION (US) | 2009-07-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110009584-A1 | Romp-Polymerizable Electron Transport Materials Based On A Bis-Oxadiazole Moiety | SLCO1B3, SLCO4C1, SLCO2B1 | KDM4E 4711/4885MAPT 834/4885ALDH1A1 1377/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.