SCHEMBL969852

SCHEMBL969852

O=C(/C=C/C(=O)OC(=O)CC(O)C(=O)O)OC(=O)CC(O)C(=O)O.[CaH2].[CaH2]

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.44
TET2 Q6N021 6/20 0.39
TET3 O43151 2/20 0.39
TET1 Q8NFU7 1/20 0.39
OR51E2 Q9H255 1/20 0.36
PGK1 P00558 1/20 0.32
PGK2 P07205 1/20 0.32
KDM4A O75164 2/20 0.32
KDM4C Q9H3R0 2/20 0.32
KDM2A Q9Y2K7 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL646454 0.98 SMN1; SMN2 (0.46) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL3716840 0.98 SMN1; SMN2 (0.46) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL27560919 0.89 SMN1; SMN2 (0.39) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL23327985 0.82 SMN1; SMN2 (0.36) SMN1; SMN2TET2TET3TET1
SCHEMBL11219458 0.82 SMN1; SMN2 (0.57) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL28622180 0.82 SMN1; SMN2 (0.43) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL7058764 0.79 HCAR2 (0.42)
SCHEMBL1533802 0.79 HCAR2 (0.42)
SCHEMBL28786289 0.78 SMN1; SMN2 (0.52) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL6863771 0.78 SMN1; SMN2 (0.52) SMN1; SMN2TET2TET3TET1OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7867526-B2 Composition for weight reduction comprising capsaicin, green tea extract, L-tyrosine and caffeine IDEASPHERE, INC. (US) 2011-01-11 US disclosed
US-20080008770-A1 Composition for weight reduction comprising capsaicin, green tea extract, L-tyrosine and caffeine MIDCAP FUNDING IV TRUST 2008-01-10 US disclosed
US-20070212430-A1 Method for weight reduction FIFTH THIRD BANK 2007-09-13 US disclosed
US-20070202200-A1 Method of inhibiting weight regain after weight loss FIFTH THIRD BANK 2007-08-30 US disclosed
US-20060240125-A1 Composition for affecting weight loss FIFTH THIRD BANK 2006-10-26 US disclosed