SCHEMBL3716840

SCHEMBL3716840

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nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 1/20 0.46
TET2 Q6N021 6/20 0.40
TET3 O43151 2/20 0.40
TET1 Q8NFU7 1/20 0.40
OR51E2 Q9H255 1/20 0.37
KDM4A O75164 2/20 0.33
KDM4C Q9H3R0 2/20 0.33
KDM2A Q9Y2K7 2/20 0.33
PGK1 P00558 1/20 0.33
PGK2 P07205 1/20 0.33
HCAR2 Q8TDS4 2/20 0.30
KMO O15229 1/20 0.30
GFPT1 Q06210 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL646454 1.00 SMN1; SMN2 (0.46) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL969852 0.98 SMN1; SMN2 (0.44) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL27560919 0.91 SMN1; SMN2 (0.39) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL23327985 0.84 SMN1; SMN2 (0.36) SMN1; SMN2TET2TET3TET1
SCHEMBL11219458 0.84 SMN1; SMN2 (0.57) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL28622180 0.83 SMN1; SMN2 (0.43) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL7058764 0.80 HCAR2 (0.42) HCAR2
SCHEMBL1533802 0.80 HCAR2 (0.42) HCAR2
SCHEMBL28786289 0.79 SMN1; SMN2 (0.52) SMN1; SMN2TET2TET3TET1OR51E2
SCHEMBL6863771 0.79 SMN1; SMN2 (0.52) SMN1; SMN2TET2TET3TET1OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0228862-B1 STABILIZED HUMAN TISSUE PLASMINOGEN ACTIVATOR COMPOSITIONS GENENTECH, INC. (US) 1992-08-12 EP claimed
CN-116847831-A Pharmaceutical composition of amorphous solid dispersion and preparation method thereof 深圳市药欣生物科技有限公司 2023-10-03 CN disclosed
US-11331305-B2 Peptides for skin rejuvenation and methods of using the same ANTEIS SA (CH) 2022-05-17 US disclosed
US-20200093799-A1 Peptides for Skin Rejuvenation and Methods of Using the Same ANTEIS SA (CH) 2020-03-26 US disclosed
CN-105189531-B Peptides for skin rejuvenation and methods of use thereof 安特易斯有限公司 2020-02-21 CN disclosed
US-10543195-B2 Peptides for skin rejuvenation and methods of using the same ANTEIS SA (CH) 2020-01-28 US disclosed
EP-2970382-B1 PEPTIDES FOR SKIN REJUVENATION AND METHODS OF USING THE SAME ANTEIS SA (CH) 2019-09-25 EP disclosed
US-9598381-B2 SMYD2 inhibitors ABBVIE INC. (US) 2017-03-21 US disclosed
US-20160271109-A1 Peptides For Skin Rejuvenation And Methods Of Using The Same ANTEIS SA (CH) 2016-09-22 US disclosed
US-9375398-B2 Peptides for skin rejuvenation and methods of using the same NEOCUTIS S.A. (CH) 2016-06-28 US disclosed
CN-1259991-A Efferescent compositions and dry effervescent granules PROCTER & GAMBLE (US) 2000-07-12 CN disclosed
WO-2000020546-A1 FOAMING SYSTEM AND DETERGENT COMPOSITIONS CONTAINING THE SAME THE PROCTER & GAMBLE COMPANY (US) 2000-04-13 WO disclosed
EP-0975723-A1 FOAMING COMPONENT THE PROCTER & GAMBLE COMPANY (US) 2000-02-02 EP disclosed
EP-0975722-A1 DETERGENT PARTICLE THE PROCTER & GAMBLE COMPANY (US) 2000-02-02 EP disclosed
EP-0975724-A1 EFFERVESCENT COMPOSITIONS AND DRY EFFERVESCENT GRANULES THE PROCTER & GAMBLE COMPANY (US) 2000-02-02 EP disclosed
WO-1999058444-A2 EFFERVESCENCE COMPONENT THE PROCTER & GAMBLE COMPANY (US) 1999-11-18 WO disclosed
WO-1998046716-A1 EFFERVESCENT COMPOSITIONS AND DRY EFFERVESCENT GRANULES THE PROCTER & GAMBLE COMPANY (US) 1998-10-22 WO disclosed
WO-1998046714-A1 DETERGENT PARTICLE THE PROCTER & GAMBLE COMPANY (US) 1998-10-22 WO disclosed
WO-1998046715-A1 FOAMING COMPONENT THE PROCTER & GAMBLE COMPANY (US) 1998-10-22 WO disclosed
US-4423057-A ANTISECRETORY, ANTICONVULSANT SYNTEX (U.S.A.) INC. (US) 1983-12-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200093799-A1 Peptides for Skin Rejuvenation and Methods of Using the Same CUTA, PLOD3, MMP13 SMN1; SMN2 3195/4885TET2 963/4885TET3 1010/4885
US-11331305-B2 Peptides for skin rejuvenation and methods of using the same CUTA, PLOD3, MMP13 SMN1; SMN2 3195/4885TET2 963/4885TET3 1010/4885
US-10543195-B2 Peptides for skin rejuvenation and methods of using the same CUTA, PLOD3, MMP13 SMN1; SMN2 3195/4885TET2 963/4885TET3 1010/4885
US-20160271109-A1 Peptides For Skin Rejuvenation And Methods Of Using The Same CUTA, PLOD3, MMP13 SMN1; SMN2 3195/4885TET2 963/4885TET3 1010/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.