SCHEMBL9698736

SCHEMBL9698736

CCC(CN(C)Cc1ccccc1)C1(CC)COC(c2nc(-c3ccccc3)c(-c3ccccc3)n2Cc2ccccc2)OC1

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
SOAT1 P35610 3/20 0.38
DNM1 Q05193 1/20 0.31
AGER Q15109 1/20 0.31
HRH3 Q9Y5N1 1/20 0.30
CFTR P13569 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9697951 0.82 SOAT1 (0.39) SOAT1
SCHEMBL9698731 0.79 SOAT1 (0.51) SOAT1
SCHEMBL9700148 0.79 SOAT1 (0.61) SOAT1
SCHEMBL9737457 0.77 SOAT1 (0.48) SOAT1CFTR
SCHEMBL9700125 0.77 SOAT1 (0.50) SOAT1
SCHEMBL9699265 0.76 SOAT1 (0.63) SOAT1
SCHEMBL9700086 0.75 SOAT1 (0.47) SOAT1
SCHEMBL9700239 0.75 SOAT1 (0.47) SOAT1
SCHEMBL9698749 0.75 SOAT1 (0.40) SOAT1HRH3
SCHEMBL9737635 0.74 SOAT1 (0.38) SOAT1CFTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992017470-A1 IMIDAZOLES RHONE-POULENC RORER LIMITED (GB) 1992-10-15 WO disclosed
EP-0506437-A1 Imidazoles RHONE POULENC RORER LIMITED (GB) 1992-09-30 EP disclosed