Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9699292 | 0.83 | KDM4E (0.40) | SOAT1ALDH1A1NPSR1TRPC5DCTPP1 | |
| SCHEMBL9698130 | 0.82 | SOAT1 (0.41) | SOAT1ALDH1A1HTTKDM4EHPGD | |
| SCHEMBL9698744 | 0.81 | SOAT1 (0.59) | SOAT1ADRA1AKCNH2HRH3 | |
| SCHEMBL9700434 | 0.80 | SOAT1 (0.33) | SOAT1ALDH1A1KDM4EHPGDTSHR | |
| SCHEMBL9737635 | 0.79 | SOAT1 (0.38) | SOAT1MEN1KMT2AALDH1A1KDM4E | |
| SCHEMBL9737457 | 0.78 | SOAT1 (0.48) | SOAT1ALDH1A1LMNAKDM4EHPGD | |
| SCHEMBL9698723 | 0.78 | SOAT1 (0.57) | SOAT1 | |
| SCHEMBL9697951 | 0.76 | SOAT1 (0.39) | SOAT1ALDH1A1NPSR1TRPC5DCTPP1 | |
| SCHEMBL9698736 | 0.75 | SOAT1 (0.38) | SOAT1HRH3 | |
| SCHEMBL9700095 | 0.74 | SOAT1 (0.43) | SOAT1ALDH1A1KDM4EHPGDTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1992017470-A1 | IMIDAZOLES | RHONE-POULENC RORER LIMITED (GB) | 1992-10-15 | — | — | WO | disclosed |
| EP-0506437-A1 | Imidazoles | RHONE POULENC RORER LIMITED (GB) | 1992-09-30 | — | — | EP | disclosed |