Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | NT5E | P21589 | 2/20 | 0.56 |
| ▸ | CASP6 | P55212 | 4/20 | 0.52 |
| ▸ | NSD2 | O96028 | 2/20 | 0.52 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.52 |
| ▸ | PTPN5 | P54829 | 2/20 | 0.52 |
| ▸ | PTPN11 | Q06124 | 2/20 | 0.52 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.47 |
| ▸ | PKLR | P30613 | 1/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31489804 | 0.89 | NSD2 (0.50) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| SCHEMBL7893085 | 0.89 | NSD2 (0.50) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| SCHEMBL27502670 | 0.88 | NSD2 (0.49) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| SCHEMBL9698775 | 0.87 | HSD17B10 (0.61) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| SCHEMBL9698048 | 0.82 | HSD17B10 (0.61) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| SCHEMBL11424222 | 0.82 | TTR (0.56) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| Sulfamide SCHEMBL11375073 | 0.79 | ALDH1A1 (0.92) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| SCHEMBL1655356 | 0.79 | TSHR (1.00) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| SCHEMBL29044 | 0.79 | TSHR (1.00) | ALDH1A1HSD17B10TSHRTDP1NT5E | |
| SCHEMBL155753 | 0.79 | HSD17B10 (0.53) | ALDH1A1HSD17B10TSHRTDP1NT5E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5116957-A | REACTIVE AZO DYESTUFFS HAVING A FLUOROTRIAZINE GROUP AND IMPROVED FIXATION PROPERTIES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-05-26 | — | — | US | disclosed |