SCHEMBL9698775

SCHEMBL9698775

Nc1cccc(S(=O)(=O)O)c1.O=S(=O)(O)c1ccc2c(O)ccc(S(=O)(=O)O)c2c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B10 Q99714 4/20 0.61
ALDH1A1 P00352 3/20 0.61
TSHR P16473 2/20 0.61
TDP1 Q9NUW8 2/20 0.61
PKLR P30613 1/20 0.52
CASP6 P55212 2/20 0.48
NT5E P21589 2/20 0.48
NSD2 O96028 1/20 0.48
DUSP3 P51452 1/20 0.48
PTPN5 P54829 1/20 0.48
PTPN11 Q06124 1/20 0.48
CA12 O43570 2/20 0.46
CA1 P00915 2/20 0.46
CA2 P00918 2/20 0.46
CA4 P22748 2/20 0.46
CA9 Q16790 2/20 0.46
CA14 Q9ULX7 1/20 0.46
HKDC1 Q2TB90 2/20 0.46
TNNI3 P19429 1/20 0.46
TNNT2 P45379 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9698048 0.94 HSD17B10 (0.61) HSD17B10ALDH1A1TSHRTDP1PKLR
SCHEMBL9698772 0.87 ALDH1A1 (0.63) HSD17B10ALDH1A1TSHRTDP1PKLR
SCHEMBL8113889 0.87 TNNI3 (0.53) HSD17B10ALDH1A1TSHRTDP1CASP6
SCHEMBL28205085 0.85 TNNI3 (0.51) HSD17B10ALDH1A1TSHRTDP1CASP6
SCHEMBL28205084 0.85 TNNI3 (0.51) HSD17B10ALDH1A1TSHRTDP1CASP6
SCHEMBL156240 0.82 NT5E (0.54) HSD17B10ALDH1A1TSHRTDP1CASP6
SCHEMBL7524251 0.80 TNNI3 (0.56) HSD17B10ALDH1A1TSHRTDP1CASP6
SCHEMBL9696625 0.80 HSD17B10 (0.54) HSD17B10ALDH1A1CASP6NT5ENSD2
SCHEMBL9698716 0.80 HSD17B10 (0.50) HSD17B10ALDH1A1TSHRCASP6NT5E
Sulfamide SCHEMBL11375073 0.78 ALDH1A1 (0.92) HSD17B10ALDH1A1TSHRTDP1PKLR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5116957-A REACTIVE AZO DYESTUFFS HAVING A FLUOROTRIAZINE GROUP AND IMPROVED FIXATION PROPERTIES BAYER AKTIENGESELLSCHAFT (DE) 1992-05-26 US disclosed